Expert-reviewed information summary about the treatment of hairy cell leukemia.
Leukemia is a broad term for cancers of the blood cells. The type of leukemia depends on the type of blood cell that becomes cancer and whether it grows quickly or slowly.
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Background Hairy-cell leukemia (HCL) is a well-defined clinicopathological entity whose underlying genetic lesion is still obscure. Methods We searched for HCL-associated mutations by performing massively parallel sequencing of the whole exome of leukemic and matched normal cells purified from the peripheral blood of an index patient with HCL.
BackgroundBRAF V600E is the genetic lesion underlying hairy-cell leukemia. We assessed the safety and activity of the oral BRAF inhibitor vemurafenib in patients with hairy-cell leukemia that had relapsed after treatment with a purine analogue or who had disease that was refractory to purine analogues.
Adult T-cell leukemia/lymphoma (ATL or ATLL) is a rare cancer of the immune system’s own T-cells.. Human T cell leukemia/lymphotropic virus type 1 is believed to be the cause of it, in addition to several other diseases.
Background: Hairy cell leukemia is an indolent B-cell leukemia comprising 2% of all leukemias, or approximately 900 of the 44,000 new cases of leukemia/year in the US
What is Leukemia? Leukemia is a type of cancer in which certain white blood cells grow out of control and spread through the blood stream.These white blood cells are made in the bone marrow.
Lymphoma and plasma cell neoplasms – Hairy cell leukemia
This slow-growing cancer doesn’t always need immediate treatment. Learn how doctors decide to start chemotherapy and biological therapy for hairy cell leukemia.